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KMID : 0644120060190040225
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Journal of Oriental Gynecology
2006 Volume.19 No. 4 p.225 ~ p.244
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A Clinical Study on the Effect of Daejo-hwan(DJH) on Climacteric Syndrome
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Kim Soo-Min
Shin Sun-Mi
Kim Eui-Il
Lee Jung-Eun
Yoo Dong-Youl
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Abstract
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Purpose : This study was performed to assess the clinical effect of Daejo-hwan(DJH) on climacteric syndrome, not only common symptoms such as hot flushes, anxiety, palpitation and so on, but also urogenital tract disturbances like vaginal dryness and sexual problems.
Methods : We randomly divided 120 women with the climacteric syndrome into two groups. One group received only DJH 2 pills(4g) a time, three times a day for 8 weeks and the other group didn’’t get any treatment for the same period. We evaluated sonography, DXA, blood test, female hormone test and questionnaires in the beginning as well as after 8 weeks of the treatment. Symptoms were measured by Kupperman’’s index, Menopausal Rating Scale and the Greene Climacteric Scale.
Results : In this study, DJH was innoxious on liver and kidney. And DJH in the treated group reduced climacteric symptoms significantly as compared to the control group without enlargement of uterus myoma and the change of estradiol. In Kupperman’’s index and MRS, DJH in the treated group especially had effects on fatigue, shoulder pain. anxiety, headache, hot flushes as well as sexual problems.
Conclusion : These results suggest that DJH can be useful in treating various climacteric symptoms including sexual problems without influences on the size of uterus myoma and estradiol.
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KEYWORD
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climacteric syndrome, Daejo-hwan, Kupperman’s index, the Greene Climacteric Scale, MRS
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